The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Dec. 10, 2009
Zheng Liu, Shanghai, CN;
Jianfeng LI, Shanghai, CN;
Xiaojun Yang, Shanghai, CN;
Zhen Wang, Shanghai, CN;
Jinfeng Zhang, Shanghai, CN;
Yi Zhu, Shandong, CN;
Guanghui Tian, Shanghai, CN;
Qing Jin, Shanghai, CN;
Jingkang Shen, Shanghai, CN;
Weiliang Zhu, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
Jingshan Shen, Shanghai, CN;
Zheng Liu, Shanghai, CN;
Jianfeng Li, Shanghai, CN;
Xiaojun Yang, Shanghai, CN;
Zhen Wang, Shanghai, CN;
Jinfeng Zhang, Shanghai, CN;
Yi Zhu, Shandong, CN;
Guanghui Tian, Shanghai, CN;
Qing Jin, Shanghai, CN;
Jingkang Shen, Shanghai, CN;
Weiliang Zhu, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
Jingshan Shen, Shanghai, CN;
Topharman Shanghai Co., Ltd., Shanghai, CN;
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Topharman Shandong Co., Ltd., Shandong, CN;
Abstract
The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following formula I, the pharmaceutically acceptable salts or solvates thereof and to the pharmaceutical composition as well as the preparation method of the compounds. The compounds of formula I according to the present invention can effectively inhibit type V phosphodiesterase (PDE5), and thus can be used for the treatment of various vascular disorders, such as male erectile dysfunction, pulmonary hypertension and the like.