The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2014

Filed:

Sep. 15, 2010
Applicants:

Christine E. Brotherton-pleiss, Sunnyvale, CA (US);

Ralph New Harris, Iii, Redwood City, CA (US);

Bradley E. Loe, Santa Cruz, CA (US);

Francisco Javier Lopez-tapia, Mahwah, NJ (US);

Pankaj D. Rege, Hoboken, NJ (US);

David Bruce Repke, Milpitas, CA (US);

Russell Stephen Stabler, Boulder Creek, CA (US);

Keith Adrian Murray Walker, Los Altos Hills, CA (US);

Inventors:

Christine E. Brotherton-Pleiss, Sunnyvale, CA (US);

Ralph New Harris, III, Redwood City, CA (US);

Bradley E. Loe, Santa Cruz, CA (US);

Francisco Javier Lopez-Tapia, Mahwah, NJ (US);

Pankaj D. Rege, Hoboken, NJ (US);

David Bruce Repke, Milpitas, CA (US);

Russell Stephen Stabler, Boulder Creek, CA (US);

Keith Adrian Murray Walker, Los Altos Hills, CA (US);

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5383 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 491/20 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 513/04 (2013.01); C07D 471/04 (2013.01); C07D 491/20 (2013.01); C07D 498/04 (2013.01);
Abstract

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein X, Y, R, R, and Rare as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.


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