The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2014

Filed:

Oct. 04, 2005
Applicants:

Mohamed F. M. Mitwally, Bloomfield Hills, MI (US);

Michael P. Diamond, Grosse Pointe Shores, MI (US);

Robert F. Casper, Toronto, CA;

Inventors:

Mohamed F. M. Mitwally, Bloomfield Hills, MI (US);

Michael P. Diamond, Grosse Pointe Shores, MI (US);

Robert F. Casper, Toronto, CA;

Assignee:

Wayne State University, Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 31/4196 (2006.01); A61K 31/5685 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/56 (2013.01); A61K 31/4196 (2013.01); A61K 31/5685 (2013.01); A61K 45/06 (2013.01);
Abstract

Aromatase inhibitors are administered to a female patient prior to endometrial ablation or resection procedures in order to thin the endometrium to a thickness of less than 6 mm, and preferably less than 4 mm, so as to enhance the treatment outcome. Of course, administration of aromatase inhibitors would be useful for other surgical procedures on the endometrial cavity and the uterus. Commercially available aromatase inhibitors, including, the nonsteroidal preparations, anastrozole and letrozole, and a steroidal agent, exemestane, are well-tolerated, and have been shown to decrease serum estrogen levels. The aromatase inhibitor can be used alone, or in combination with other aromatase inhibitors or pharmaceutical agents, such as hormones.


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