The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Sep. 19, 2011
David Bernard Smith, San Mateo, CA (US);
Jerome Deval, Pacifica, CA (US);
Natalia Dyatkina, Mountain View, CA (US);
Leonid Beigelman, San Mateo, CA (US);
Guangyi Wang, Carlsbad, CA (US);
David Bernard Smith, San Mateo, CA (US);
Jerome Deval, Pacifica, CA (US);
Natalia Dyatkina, Mountain View, CA (US);
Leonid Beigelman, San Mateo, CA (US);
Guangyi Wang, Carlsbad, CA (US);
Alios BioPharma, Inc., South San Francisco, CA (US);
Abstract
Disclosed herein are phosphorothioate nucleotide analogs, such as thiophosphoroamidate prodrugs and thiophosphates (including α-thiomonophosphates, α-thiodiphosphates, and α-thiotriphosphates), methods of synthesizing phosphorothioate nucleotide analogs, such as thiophosphoramidate prodrugs, and thiophosphates and methods of treating viral infections, such as HCV, cancer, and/or parasitic diseases with the phosphorothioate nucleotide analogs, such as thiophosphoramidate prodrugs, and thiophosphates.