The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Mar. 16, 2012
Stefanie Dimmeler, Frankfurt, DE;
Reinier A. Boon, Frankfurt, DE;
Ariane Fischer, Frankfurt, DE;
Andreas M. Zeiher, Frankfurt, DE;
Stefanie Dimmeler, Frankfurt, DE;
Reinier A. Boon, Frankfurt, DE;
Ariane Fischer, Frankfurt, DE;
Andreas M. Zeiher, Frankfurt, DE;
Migagen Therapeutics, Inc., Boulder, CO (US);
Abstract
The present invention relates to treating or preventing age-related cardiomyopathy by modulating the expression or activity of a miR-34 family member and/or PNUTS. Methods of treating or preventing age-related cardiomyopathy include administering an inhibitor of miR-34 expression or activity or an agonist of PNUTS expression or activity. Also provided herein are methods of treating or preventing cardiac fibrosis and myocardial infarction by administering an inhibitor of miR-34 expression or activity or an agonist of PNUTS expression or activity.