The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Mar. 28, 2007
Applicants:
Stephen Hyde, Oxford, GB;
Deborah Gill, Oxford, GB;
Inventors:
Stephen Hyde, Oxford, GB;
Deborah Gill, Oxford, GB;
Assignee:
Isis Innovation Limited, Oxford, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C07H 21/00 (2006.01); A61K 48/00 (2006.01); C12N 15/67 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/67 (2013.01); A61K 48/0058 (2013.01); C12N 15/85 (2013.01); C12N 2830/00 (2013.01);
Abstract
A promoter for high level and sustained expression is provided which can be used for gene expression of chosen sequences in general. In particular, a nucleic acid construct comprising a hCEF1 promoter operably linked to a sequence for expression is provided, where the hCEF1 promoter comprises: (i) a human CMV enhancer operably linked to a human EF1 a promoter; (ii) a functional fragment of (i); or (ii) a functional variant of (i) or (ii).