The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Aug. 20, 2009
Gregory J. Sommer, Livermore, CA (US);
Anson V. Hatch, Tracy, CA (US);
Anup K. Singh, Danville, CA (US);
Ying-chih Wang, Pleasanton, CA (US);
Gregory J. Sommer, Livermore, CA (US);
Anson V. Hatch, Tracy, CA (US);
Anup K. Singh, Danville, CA (US);
Ying-Chih Wang, Pleasanton, CA (US);
Sandia Corporation, Albuquerque, NM (US);
Abstract
Embodiments of the present invention provide methods, microfluidic devices, and systems for the detection of an active target agent in a fluid sample. A substrate molecule is used that contains a sequence which may cleave in the presence of an active target agent. A SNAP25 sequence is described, for example, that may be cleaved in the presence of Botulinum Neurotoxin. The substrate molecule includes a reporter moiety. The substrate molecule is exposed to the sample, and resulting reaction products separated using electrophoretic separation. The elution time of the reporter moiety may be utilized to identify the presence or absence of the active target agent.