The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Jun. 05, 2013
Applicant:
Zymogenetics, Inc., Princeton, NJ (US);
Inventors:
Stephen R. Jaspers, Brewster, NY (US);
Scott R. Presnell, Tacoma, WA (US);
Monica J. Huber, Bothell, WA (US);
Assignee:
ZymoGenetics, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); C12N 15/13 (2006.01); C12P 21/08 (2006.01); C07K 16/46 (2006.01); C07K 16/24 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); C07K 16/244 (2013.01); Y10S 530/809 (2013.01); G01N 2333/54 (2013.01); G01N 33/6869 (2013.01); C07K 2316/96 (2013.01); A61K 2039/505 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. The present invention includes antibodies that bind both IL-17A and IL-17F, hybridomas that produce the antibodies, and methods of using the same in inflammation.