The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Feb. 24, 2012
Applicants:
Alice Y. Ting, Allston, MA (US);
Marta Fernandez Suarez, Cambridge, MA (US);
Hemanta Baruah, Cambridge, MA (US);
Inventors:
Alice Y. Ting, Allston, MA (US);
Marta Fernandez Suarez, Cambridge, MA (US);
Hemanta Baruah, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12N 9/12 (2006.01); A61K 38/00 (2006.01); C07H 21/04 (2006.01); G01N 33/533 (2006.01); C12N 9/00 (2006.01); G01N 33/532 (2006.01); C12N 15/62 (2006.01); C07K 4/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/533 (2013.01); C12N 9/1241 (2013.01); G01N 2333/9015 (2013.01); C12N 15/62 (2013.01); C07K 4/00 (2013.01); C12N 9/93 (2013.01); G01N 33/532 (2013.01);
Abstract
The invention provides compositions and methods of use thereof for labeling peptide and proteins in vitro or in vivo. The methods described herein employ lipoic acid ligase or mutants thereof, and lipoic acid analogs recognized by lipoic acid ligase and lipoic acid ligase mutants.