The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Jul. 16, 2010
Applicants:
Laura Serino, Siena, IT;
Danilo Gomes Moriel, Montariggioni, IT;
Maria Rita Fontana, Siena, IT;
Inventors:
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); C07K 1/00 (2006.01); C12N 1/20 (2006.01); C07H 21/04 (2006.01); C07K 14/245 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/245 (2013.01); A61K 39/00 (2013.01);
Abstract
Detoxified variants of the pathogenic'AcfD precursor' (orf3526) have been identified that raise a substantially similar immune response in a subject as the native AcfD (orB526) protein. The detoxified variants may be further modified to have increased solubility as compared to the native AcfD (orf3526) protein.