The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

May. 12, 2010
Applicants:

Marc Van DE Craen, Aalter, BE;

Phuay-yee Goh, Singapore, SG;

Marc Georges Logghe, St Denijs Westrem, BE;

Yee-ling Khu, Singapore, SG;

Katherine an Hilde Mortier, Ghent, BE;

Thierry Andre Oliver Eddy Bogaert, Kortrijk, BE;

Inventors:

Marc Van De Craen, Aalter, BE;

Phuay-Yee Goh, Singapore, SG;

Marc Georges Logghe, St Denijs Westrem, BE;

Yee-Ling Khu, Singapore, SG;

Katherine An Hilde Mortier, Ghent, BE;

Thierry Andre Oliver Eddy Bogaert, Kortrijk, BE;

Assignee:

Devgen NV, Zwijnaarde, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 15/87 (2006.01); C07H 21/04 (2006.01); C07K 14/37 (2006.01); A01N 63/02 (2006.01); A01N 63/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8218 (2013.01); C07K 14/37 (2013.01); A01N 63/02 (2013.01); A01N 63/04 (2013.01); C12N 15/8282 (2013.01);
Abstract

The present invention concerns methods for controlling fungus infestation via dsRNA mediated gene silencing, whereby the intact fungus cell(s) are contacted with a double-stranded RNA from outside the fungal cell(s) and whereby the double-stranded RNA is taken up by the intact fungal cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from fungus pests. Alternatively, the methods are used for treating and/or preventing fungal infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable fungal target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.


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