The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Nov. 19, 2009
Applicants:

Morris Srebnik, Mevasseret Zion, IL;

Itzhack Polacheck, Jerusalem, IL;

Doron Steinberg, Jerusalem, IL;

Adel Jabbour, Nazareth Ilit, IL;

Edward Sionov, Azur, IL;

Inventors:

Morris Srebnik, Mevasseret Zion, IL;

Itzhack Polacheck, Jerusalem, IL;

Doron Steinberg, Jerusalem, IL;

Adel Jabbour, Nazareth Ilit, IL;

Edward Sionov, Azur, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/34 (2006.01); A01N 43/76 (2006.01); C08G 65/334 (2006.01); C07D 207/448 (2006.01); A01N 43/50 (2006.01); C08F 228/06 (2006.01); A01N 37/32 (2006.01); C08F 222/40 (2006.01); C08G 65/333 (2006.01); A01N 43/78 (2006.01); C08F 220/14 (2006.01); C08F 220/56 (2006.01);
U.S. Cl.
CPC ...
C07D 277/34 (2013.01); A01N 43/76 (2013.01); C08G 65/3348 (2013.01); C07D 207/448 (2013.01); C08F 220/14 (2013.01); A01N 43/50 (2013.01); C08F 228/06 (2013.01); A01N 37/32 (2013.01); C08F 222/40 (2013.01); C08G 65/33337 (2013.01); C08F 220/56 (2013.01); A01N 43/78 (2013.01);
Abstract

Novel agents exhibiting anti-biofilm formation activity while being non-cytotoxic are provided, as well as methods of using the same, either per se or conjugated to a polymer, for preventing and/or reducing the formation of microbial biofilms and/or for disrupting microbial biofilms. The novel agents described herein include thiazolidine-2,4-diones (TZDs), pyrrolidine-2,5-diones (PYDs), imidazolidine-2,4-diones or oxazolidine-2,4-diones, substituted by an alkyl having 7-20 carbon atoms in its backbone chain.


Find Patent Forward Citations

Loading…