The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
Sep. 13, 2012
Schuyler Corry, Eugene, OR (US);
William Downey, Eugene, OR (US);
Brian Filanoski, Eugene, OR (US);
Kyle Gee, Springfield, OR (US);
Lawrence Greenfield, Eugene, OR (US);
James Hirsch, Springfield, OR (US);
Iain Johnson, Eugene, OR (US);
Aleksey Rukavishnikov, Eugene, OR (US);
Schuyler Corry, Eugene, OR (US);
William Downey, Eugene, OR (US);
Brian Filanoski, Eugene, OR (US);
Kyle Gee, Springfield, OR (US);
Lawrence Greenfield, Eugene, OR (US);
James Hirsch, Springfield, OR (US);
Iain Johnson, Eugene, OR (US);
Aleksey Rukavishnikov, Eugene, OR (US);
Life Technologies Corporation, Carlsbad, CA (US);
Abstract
The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactamase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactamase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactamase or instructions for using the components in an assay.