The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
Jan. 18, 2013
Applicant:
Genzyme Corporation, Cambridge, MA (US);
Inventors:
Michele Youd, Lexington, MA (US);
Jennifer Tedstone, Hopkinton, MA (US);
Tracey Lodie, Northbridge, MA (US);
Karen B. Carter, Fiskdale, MA (US);
Timothy D. Connors, Shrewsbury, MA (US);
Jason Robert Pinckney, Marlborough, MA (US);
Elizabeth Masterjohn, Hudson, MA (US);
Ruiyin Chu, Belle Mead, NJ (US);
Assignee:
Genzyme Corporation, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); C07K 17/00 (2006.01); C07K 17/14 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); C07K 2317/565 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 2317/92 (2013.01); C07K 2317/34 (2013.01); C07K 2317/24 (2013.01);
Abstract
The present disclosure provides anti-CXCR3 antibodies and methods of using the antibodies to diagnose and/or treat CXCR3-associated disorders such as diabetes mellitus type I (T1D), particularly new-onset T1D. In certain embodiments, disclosed herein are CXCR3 neutralizing antibodies.