The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
Oct. 29, 2009
Applicants:
Torsten Steinmetzer, Jena, DE;
Gero Becker, Marburg, DE;
Wolfgang Garten, Giessen, DE;
Inventors:
Assignee:
Philipps-Universitat Marburg, Marburg, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/10 (2006.01); A61K 38/07 (2006.01); C07K 5/083 (2006.01); C07K 5/09 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0808 (2013.01); A61K 38/00 (2013.01); C07K 5/0815 (2013.01); C07K 5/0817 (2013.01);
Abstract
The invention refers to multibasic, N-terminally modified tetrapeptide mimetics with a C-terminal P1-arginine mimetic, methods for their production and use for therapy and prophylaxis of diseases, caused by bacterial pathogens or viruses, as well as for therapy and prophylaxis of diabetes, arteriosclerosis, cancer, Alzheimer's or the onset of obesity, as well as the use of these compounds as inhibitors of the proprotein convertases which cleave behind basic P1 residues, especially for inhibition of the protease furin.