The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Feb. 14, 2012
Applicants:

Zilin Huang, San Leandro, CA (US);

Jeff Jin, San Ramon, CA (US);

Timothy Machajewski, Martinez, CA (US);

William R. Antonios-mccrea, Moraga, CA (US);

Maureen Mckenna, Pinole, CA (US);

Daniel Poon, Piedmont, CA (US);

Paul A. Renhowe, Sudbury, MA (US);

Martin Sendzik, San Mateo, CA (US);

Cynthia Shafer, Moraga, CA (US);

Aaron Smith, Union City, CA (US);

Yongjin Xu, Castro Valley, CA (US);

Qiong Zhang, Union City, CA (US);

Zheng Chen, Fremont, CA (US);

Inventors:

Zilin Huang, San Leandro, CA (US);

Jeff Jin, San Ramon, CA (US);

Timothy Machajewski, Martinez, CA (US);

William R. Antonios-McCrea, Moraga, CA (US);

Maureen McKenna, Pinole, CA (US);

Daniel Poon, Piedmont, CA (US);

Paul A. Renhowe, Sudbury, MA (US);

Martin Sendzik, San Mateo, CA (US);

Cynthia Shafer, Moraga, CA (US);

Aaron Smith, Union City, CA (US);

Yongjin Xu, Castro Valley, CA (US);

Qiong Zhang, Union City, CA (US);

Zheng Chen, Fremont, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 241/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.


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