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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8865731 B1

PDFFull Text
Date of Patent:
Oct. 21, 2014

Filed:

May. 29, 2009

Inhibitor of analgesic tolerance

Applicants:

Jun Ouchi, Shizuoka, JP;

Shunji Kunori, Shizuoka, JP;

Yozo Kojima, Shizuoka, JP;

Katsumi Shinoda, Tokyo, JP;

Katsutoshi Sasaki, Shizuoka, JP;

Shiro Shirakura, Shizuoka, JP;

Inventors:

Jun Ouchi, Shizuoka, JP;

Shunji Kunori, Shizuoka, JP;

Yozo Kojima, Shizuoka, JP;

Katsumi Shinoda, Tokyo, JP;

Katsutoshi Sasaki, Shizuoka, JP;

Shiro Shirakura, Shizuoka, JP;

Assignee:

Kyowa Hakko Kirin Co., Ltd., Tokyo, JP;

Attorney:

Fitzpatrick, Cella, Harper & Scinto

Primary Examiner:

Kendra D Carter

Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/522 (2006.01); A61K 31/52 (2006.01); A01N 43/64 (2006.01); A61K 31/41 (2006.01); A01N 43/78 (2006.01); A61K 31/425 (2006.01); A01N 43/54 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); C07D 471/04 (2006.01); C07D 471/22 (2006.01); C07D 487/04 (2006.01); C07D 473/00 (2006.01); C07D 273/00 (2006.01); C07D 239/02 (2006.01); C07D 249/16 (2006.01); C07D 403/00 (2006.01); A61K 31/4439 (2006.01); C07D 473/34 (2006.01); C07D 473/06 (2006.01); C07D 487/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61K 31/343 (2006.01); A61K 31/427 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61K 31/522 (2013.01); A61K 31/4439 (2013.01); C07D 473/34 (2013.01); C07D 473/06 (2013.01); C07D 487/14 (2013.01); C07D 417/04 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); A61K 31/343 (2013.01); C07D 487/04 (2013.01); A61K 31/52 (2013.01); A61K 31/427 (2013.01); A61K 31/519 (2013.01); A61K 31/485 (2013.01);
Abstract

Provided are: an agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), which comprises a compound having adenosine Areceptor antagonistic activity or a pharmaceutically acceptable salt thereof as an active ingredient; the agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), wherein the undesirable effect of the opioid-type analgesic (opioid) is analgesic tolerance or constipation; the agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), wherein the undesirable effect of the opioid-type analgesic (opioid) is analgesic tolerance; and the like.

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