The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Sep. 03, 2010
Applicants:

Steven W. Andrews, Boulder, CO (US);

Kevin Ronald Condroski, Wallingford, CT (US);

Lisa A. DE Meese, Chandler, AZ (US);

Jay Bradford Fell, Boulder, CO (US);

John P. Fischer, Boulder, CO (US);

John A. Josey, Dallas, TX (US);

Kevin Koch, Boulder, CO (US);

Yvan Le Huerou, Boulder, CO (US);

Gregory F. Miknis, Broomfield, CO (US);

Martha E. Rodriguez, Lafayette, CO (US);

George T. Topalov, Superior, CO (US);

Eli M. Wallace, Richardson, TX (US);

Rui Xu, Boulder, CO (US);

Inventors:

Steven W. Andrews, Boulder, CO (US);

Kevin Ronald Condroski, Wallingford, CT (US);

Lisa A. De Meese, Chandler, AZ (US);

Jay Bradford Fell, Boulder, CO (US);

John P. Fischer, Boulder, CO (US);

John A. Josey, Dallas, TX (US);

Kevin Koch, Boulder, CO (US);

Yvan Le Huerou, Boulder, CO (US);

Gregory F. Miknis, Broomfield, CO (US);

Martha E. Rodriguez, Lafayette, CO (US);

George T. Topalov, Superior, CO (US);

Eli M. Wallace, Richardson, TX (US);

Rui Xu, Boulder, CO (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

Compounds of Formula I: and salts thereof in which R, R, R, R, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.


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