The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Oct. 14, 2013
Applicants:

Kristof Van Emelen, Sint-Niklaas, BE;

Janine Arts, GM Breda, NL;

Leo-jacobus Jozef Backx, Arendonk, BE;

Hans Louis Jos DE Winter, Schilde, BE;

Sven Franciscus Anna Van Brandt, Nijlen, BE;

Marc Gustaaf Celine Verdonck, Gierle, BE;

Lieven Meerpoel, Beerse, BE;

Isabelle Noelle Constance Pilatte, Louviers, FR;

Virginie Sophie Poncelet, Le Marier sur Seine, FR;

Alexey Borisovich Dyatkin, Ambler, PA (US);

Jimmy Arnold Viviane Van Heusden, Oelegem, BE;

Inventors:

Kristof Van Emelen, Sint-Niklaas, BE;

Janine Arts, GM Breda, NL;

Leo-Jacobus Jozef Backx, Arendonk, BE;

Hans Louis Jos De Winter, Schilde, BE;

Sven Franciscus Anna Van Brandt, Nijlen, BE;

Marc Gustaaf Celine Verdonck, Gierle, BE;

Lieven Meerpoel, Beerse, BE;

Isabelle Noelle Constance Pilatte, Louviers, FR;

Virginie Sophie Poncelet, Le Marier sur Seine, FR;

Alexey Borisovich Dyatkin, Ambler, PA (US);

Jimmy Arnold Viviane Van Heusden, Oelegem, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/28 (2006.01); C07D 409/04 (2006.01); C07D 213/82 (2006.01); C07D 233/90 (2006.01); C07D 413/14 (2006.01); C07D 307/79 (2006.01); C07D 213/81 (2006.01); C07D 243/08 (2006.01); G01N 33/573 (2006.01); C07D 333/34 (2006.01); A61K 31/495 (2006.01); C07D 295/22 (2006.01); A61K 45/06 (2006.01); C07D 241/24 (2006.01); C07D 403/04 (2006.01); C07D 239/42 (2006.01); A61K 31/496 (2006.01); C07D 241/04 (2006.01); C07D 295/26 (2006.01); C07D 207/277 (2006.01); C07D 261/10 (2006.01);
U.S. Cl.
CPC ...
C07D 295/26 (2013.01); G01N 2333/91 (2013.01); C07D 307/79 (2013.01); C07D 213/81 (2013.01); C07D 243/08 (2013.01); C07D 409/04 (2013.01); C07D 207/28 (2013.01); G01N 33/573 (2013.01); C07D 333/34 (2013.01); A61K 31/495 (2013.01); C07D 295/22 (2013.01); C07D 233/90 (2013.01); A61K 45/06 (2013.01); C07D 241/24 (2013.01); C07D 403/04 (2013.01); C07D 239/42 (2013.01); A61K 31/496 (2013.01); C07D 241/04 (2013.01); C07D 207/277 (2013.01); C07D 261/10 (2013.01); C07D 213/82 (2013.01); C07D 413/14 (2013.01);
Abstract

This invention comprises the novel compounds of formula (I) wherein n, m, t, R, R, R, R, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.


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