The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Feb. 14, 2013
Applicants:

Christian Eickmeier, Mittelbiberach, DE;

Kai Gerlach, Mittelbiberach, DE;

Niklas Heine, Biberach an der Riss, DE;

Alexander Weber, Biberach an der Riss, DE;

Ulrike Gross, Biberach an der Riss, DE;

Inventors:

Christian Eickmeier, Mittelbiberach, DE;

Kai Gerlach, Mittelbiberach, DE;

Niklas Heine, Biberach an der Riss, DE;

Alexander Weber, Biberach an der Riss, DE;

Ulrike Gross, Biberach an der Riss, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/58 (2006.01); A01N 43/60 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01); C07D 475/00 (2006.01); A61K 31/519 (2006.01); C07D 491/20 (2006.01); C07D 475/12 (2006.01);
U.S. Cl.
CPC ...
C07D 491/20 (2013.01); A61K 31/519 (2013.01); C07D 475/00 (2013.01); C07D 475/12 (2013.01);
Abstract

The present invention relates to spiroheterocycl-dihydropyrimidines, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of Aβ peptides.


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