The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
Oct. 12, 2011
Applicants:
Dieter Dorsch, Ober-Ramstadt, DE;
Margarita Wucherer-plietker, Messel, DE;
Thomas J. J. Mueller, Duesseldorf, DE;
Eugen Merkul, Duesseldorf, DE;
Inventors:
Dieter Dorsch, Ober-Ramstadt, DE;
Margarita Wucherer-Plietker, Messel, DE;
Thomas J. J. Mueller, Duesseldorf, DE;
Eugen Merkul, Duesseldorf, DE;
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 487/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4985 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention relates to compounds the formula (I): and pharmaceutically usable salts, tautomers and stereoisomers thereof, wherein R, Rand Rare defined herein. The compounds of formula (I) and their pharmaceutically usable salts, tautomers and stereoisomers are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.