The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
Sep. 07, 2012
Applicants:
Michael Detmar, Boppelsen, CH;
Kentaro Kajiya, Yokohama, JP;
Inventors:
Michael Detmar, Boppelsen, CH;
Kentaro Kajiya, Yokohama, JP;
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 14/475 (2006.01); G01N 33/50 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1833 (2013.01); G01N 33/5064 (2013.01); G01N 2333/4753 (2013.01);
Abstract
Provided are methods and compositions for the modulation of hepatocyte growth factor activity to regulate lymphatic vessel development and function. Methods and composition for the monitoring and treatment of skin disorders, lymphedema, and metastatic cancers are disclosed. Also described are methods of identifying inhibitors of hepatocyte growth factor dependent lymphangiogenesis.