The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Aug. 13, 2010
Applicants:

Johannes Laurenz Kellenberger, Riehen, CH;

Jürg Dreier, Witterswil, CH;

Inventors:

Johannes Laurenz Kellenberger, Riehen, CH;

Jürg Dreier, Witterswil, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/706 (2006.01); C07H 17/08 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07H 17/08 (2013.01);
Abstract

The invention relates to macrolide compounds of formula (I), the use of said compounds as medicaments, in particular for the treatment or prevention of inflammatory and allergic diseases, pharmaceutical compositions containing said compounds and to processes for their preparation. The invention relates in particular to macrolide compounds with antiinflammatory activity mediated primarily through inhibition of phosphodiesterase 4 (PDE4) which makes them useful for the treatment and/or prevention of inflammatory and allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rheumatoid arthritis, atopic dermatitis or inflammatory bowel disease or proliferative diseases such as cancer.


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