The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2014
Filed:
Nov. 22, 2007
Arasu Ganesan, Hampshire, GB;
Graham Keith Packham, Wiltshire, GB;
Alexander Richard Liam Cecil, Hampshire, GB;
Arasu Ganesan, Hampshire, GB;
Graham Keith Packham, Wiltshire, GB;
Alexander Richard Liam Cecil, Hampshire, GB;
Karus Therapeutics Limited, Hampshire, GB;
Abstract
A compound of the general Structure (VII) or (VIII) including isoteres and pharmaceutically acceptable salts thereof, wherein R, R(where X=—CONR—), Rand Rare the same or different and each represents an amino-acid side chain moiety; R(where X=—CHZ—), Rand Rare the same or different and each represents hydrogen, C-Calkyl, C-Calkenyl, or C-Calkynyl; K represents a linear or branched chain of carbon atoms and containing 1-10 atoms; L represents a moiety capable of chelating zinc in the active site of a histone deacetylase (HDAC) or of conversion to such a moiety in vivo (by hydrolysis or reduction, for example); M is a linear or branched chain of carbon or other atoms and containing 1-10 atoms, and capable of undergoing in vivo cleavage to give Structure (VII); and Z is a heteroatom bonded to the macrocycle by a single or double bond, and any other group bonded to Z is H or a protecting group.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile