The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Aug. 27, 2012
Applicants:

Ramon E. Poo, Miami, FL (US);

Camillo Ricordi, Miami, FL (US);

Felipe Echeverri, Miami, FL (US);

Over Cabrera, Deerfield Beach, FL (US);

Per-olof Berggren, Miami, FL (US);

Inventors:

Ramon E. Poo, Miami, FL (US);

Camillo Ricordi, Miami, FL (US);

Felipe Echeverri, Miami, FL (US);

Over Cabrera, Deerfield Beach, FL (US);

Per-Olof Berggren, Miami, FL (US);

Assignees:

Biorep Technologies, Inc., Miami, FL (US);

University of Miami, Miami, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); C12M 3/00 (2006.01); C12M 1/34 (2006.01); C12M 1/00 (2006.01); C12M 1/32 (2006.01);
U.S. Cl.
CPC ...
C23M 41/48 (2013.01); C12M 23/42 (2013.01); C12M 41/00 (2013.01); C12M 23/40 (2013.01); C12M 23/12 (2013.01);
Abstract

A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A manifold having a plurality of liquid inlets, control valves, and liquid outlets can be provided. A receptacle housing has a plurality of receptacles. A drive is connected to the receptacle housing for moving the receptacle housing. A programmable controller can be provided to control movement of the receptacle housing. The test liquid includes at least one stimuli for the cells. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.


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