The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Apr. 10, 2008
Applicants:

Hidetaka Akatsuka, Yokohama, JP;

Hitoshi Imamura, Yokohama, JP;

Yasuyuki Ishihara, Yokohama, JP;

Inventors:

Hidetaka Akatsuka, Yokohama, JP;

Hitoshi Imamura, Yokohama, JP;

Yasuyuki Ishihara, Yokohama, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 8/44 (2006.01); A61K 8/41 (2006.01); A61K 8/64 (2006.01); A61K 8/34 (2006.01); A61K 36/00 (2006.01); A61K 8/68 (2006.01); A61K 8/63 (2006.01); A61K 8/14 (2006.01); A61K 31/56 (2006.01); A61K 8/60 (2006.01); A61Q 19/00 (2006.01); A61K 8/97 (2006.01); A61K 8/67 (2006.01); A61K 31/05 (2006.01); A61K 31/352 (2006.01); A61K 8/39 (2006.01); A61K 31/7048 (2006.01); A61K 8/86 (2006.01); A61K 8/368 (2006.01); A61K 8/37 (2006.01); A61K 8/49 (2006.01); A61K 31/16 (2006.01); A61K 31/164 (2006.01); A61K 31/19 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0014 (2013.01); A61K 8/44 (2013.01); A61K 8/41 (2013.01); A61K 8/64 (2013.01); A61K 8/347 (2013.01); A61K 36/00 (2013.01); A61K 8/68 (2013.01); A61K 8/63 (2013.01); A61K 8/14 (2013.01); A61K 31/56 (2013.01); A61K 8/602 (2013.01); A61Q 19/00 (2013.01); A61K 8/97 (2013.01); A61K 8/676 (2013.01); A61K 8/975 (2013.01); A61K 31/05 (2013.01); A61K 31/352 (2013.01); A61K 8/39 (2013.01); A61K 31/7048 (2013.01); A61K 8/86 (2013.01); A61K 8/368 (2013.01); A61K 8/375 (2013.01); A61K 8/498 (2013.01); A61K 31/16 (2013.01); A61K 31/164 (2013.01); A61K 31/19 (2013.01);
Abstract

Disclosed is a technique for allowing an active ingredient as an agent for improving or maintaining the dermal environment to reach a dermis. Specifically disclosed is a vesicle comprising the following components 1) to 3): 1) an α,ε-bis(γ-N—(C)acylglutamyl)lysine and/or a salt thereof; 2) ceramide and/or a derivative thereof; and 3) one or more selected from a glycerin fatty acid ester, a polyglycerin fatty acid ester and a pyroglutamic acid glycerin fatty acid ester. The acyl group in the α,ε-bis(γ-N—(C)acylglutamyl)lysine is preferably a lauroyl group. The ceramide or the derivative thereof is preferably ceramide type-2 or ceramide type-3. The vesicle can encapsulate an active ingredient. The vesicle can be contained in an external preparation for the skin.


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