The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Jul. 30, 2010
Applicants:

Timothy P. Mayall, Encinitas, CA (US);

Jeff Alexander, San Diego, CA (US);

Inventors:

Timothy P. Mayall, Encinitas, CA (US);

Jeff Alexander, San Diego, CA (US);

Assignee:

Paxvax, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/235 (2006.01); A61K 39/295 (2006.01); C12N 15/86 (2006.01); A61K 39/145 (2006.01); A61K 31/713 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 2039/5256 (2013.01); C12N 15/86 (2013.01); A61K 39/145 (2013.01); C12N 2760/16134 (2013.01); C12N 7/00 (2013.01); C12N 2710/10343 (2013.01);
Abstract

The present invention provides replication competent adenoviral vectors capable of expressing antigens from infectious pathogens, such as influenza virus. The adenoviral vectors can be used to vaccinate subjects against the infectious pathogens. The adenoviral vectors comprise heterologous sequences encoding the antigens. The heterologous sequences can be inserted into various locations in the adenoviral vectors, including in or near specific E3 deletions and/or integrated into the adenoviral hexon coding region. The adenoviral vectors can be derived from any adenoviral serotype, particularly an Ad4 or Ad7 serotype.


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