The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2014

Filed:

Apr. 23, 2008
Applicants:

Suzanne M. Spong, San Francisco, CA (US);

Thomas B. Neff, Atherton, CA (US);

Stephen J. Klaus, San Francisco, CA (US);

Inventors:

Suzanne M. Spong, San Francisco, CA (US);

Thomas B. Neff, Atherton, CA (US);

Stephen J. Klaus, San Francisco, CA (US);

Assignee:

Fibrogen, Inc., San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 14/71 (2006.01); C07K 16/22 (2006.01); A61K 45/06 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 39/395 (2013.01); A61K 39/39558 (2013.01); C07K 14/71 (2013.01); C07K 16/22 (2013.01); G01N 2333/475 (2013.01); A61K 2039/505 (2013.01); A61K 45/06 (2013.01); G01N 33/57438 (2013.01);
Abstract

The present invention provides methods for reducing tumor survival, expansion, and metastasis. In particular, the invention provides methods for reducing pancreatic tumor survival, expansion, and metastasis. The invention also provides agents for use in the methods, particularly agents that reduce the level or activity of connective tissue growth factor (CTGF), and methods for identifying such agents.


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