The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Apr. 23, 2013
Applicant:

Duke University, Durham, NC (US);

Inventors:

Adam Wax, Chapel Hill, NC (US);

John W. Pyhtila, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01B 9/02 (2006.01); G01J 3/45 (2006.01); G01N 21/31 (2006.01); A61B 5/00 (2006.01); G01N 21/47 (2006.01);
U.S. Cl.
CPC ...
G01J 3/45 (2013.01); A61B 5/0084 (2013.01); G01B 9/02087 (2013.01); G01N 2021/4735 (2013.01); A61B 5/0066 (2013.01); G01N 21/4795 (2013.01); G01N 21/31 (2013.01); G01N 2201/08 (2013.01); G01B 9/0209 (2013.01); G01N 2021/4704 (2013.01); G01N 2021/4709 (2013.01); A61B 5/0075 (2013.01); G01B 9/02044 (2013.01); G01B 9/02084 (2013.01);
Abstract

Fourier domain a/LCI (faLCI) system and method which enables in vivo data acquisition at rapid rates using a single scan. Angle-resolved and depth resolved spectra information is obtained with one scan. The reference arm can remain fixed with respect to the sample due to only one scan required. A reference signal and a reflected sample signal are cross-correlated and dispersed at a multitude of reflected angles off of the sample, thereby representing reflections from a multitude of points on the sample at the same time in parallel. Information about all depths of the sample at each of the multitude of different points on the sample can be obtained with one scan on the order of approximately 40 milliseconds. From the spatial, cross-correlated reference signal, structural (size) information can also be obtained using techniques that allow size information of scatterers to be obtained from angle-resolved data.


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