The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Jul. 12, 2013
Applicant:
Euclises Pharmaceuticals, Inc., St. Louis, MO (US);
Inventors:
Eduardo J. Martinez, Bryn Mawr, PA (US);
John J. Talley, St. Louis, MO (US);
Kevin D. Jerome, St. Charles, MO (US);
Terri L. Boehm, Ballwin, MO (US);
Assignee:
Euclises Pharmaceuticals, Inc., St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/10 (2006.01); C07D 403/14 (2006.01); C07D 403/12 (2006.01); C07D 231/12 (2006.01);
U.S. Cl.
CPC ...
C07D 231/12 (2013.01); C07D 403/14 (2013.01); C07D 403/12 (2013.01);
Abstract
The present invention provides NO-releasing NONOate(nitrogen bound)sulfonamide-linked-coxib anti-cancer agents, having the structure of Formula (I): wherein R, X, L, R, R, R, and Z are as defined in the detailed description; pharmaceutical compositions comprising at least one compound of Formula (I); and methods useful for healing wounds, preventing and treating cancer, or treating actinic keratosis, cystic fibrosis or acne, using a compound of Formula (I).