The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Aug. 10, 2011
Applicants:

Courtney A. Cullis, Bedford, MA (US);

Krista E. Granger, Medford, MA (US);

Jianping Guo, Winchester, MA (US);

Masaaki Hirose, Kanagawa, JP;

Gang LI, Westborough, MA (US);

Miho Mizutani, Cambridge, MA (US);

Tricia J. Vos, Winchester, MA (US);

Inventors:

Courtney A. Cullis, Bedford, MA (US);

Krista E. Granger, Medford, MA (US);

Jianping Guo, Winchester, MA (US);

Masaaki Hirose, Kanagawa, JP;

Gang Li, Westborough, MA (US);

Miho Mizutani, Cambridge, MA (US);

Tricia J. Vos, Winchester, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/02 (2006.01); C07D 241/02 (2006.01); C07D 213/22 (2006.01); C07D 413/00 (2006.01); C07D 401/00 (2006.01); A61K 31/505 (2006.01); A61K 31/44 (2006.01); A61K 31/42 (2006.01); A61K 31/422 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/422 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 413/04 (2013.01);
Abstract

This invention provides compounds of formula IA or IB: wherein HY, R, R, and G, are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.


Find Patent Forward Citations

Loading…