The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Dec. 19, 2012
Board of Regents, the University of Texas System, Austin, TX (US);
Jacki Lin, Boston, MA (US);
Ralph Arlinghaus, Bellaire, TX (US);
Tong Sun, Pearland, TX (US);
Lin Ji, Sugar Land, TX (US);
Bulent Ozpolat, Houston, TX (US);
Gabriel Lopez-Berestein, Bellaire, TX (US);
Jack A. Roth, Houston, TX (US);
The Board of Regents of the University of Texas System, Austin, TX (US);
Abstract
A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.