The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Nov. 28, 2008
Applicants:
Carsten Werner, Dresden, DE;
Uwe Freudenberg, Dresden, DE;
Dorit Meinhold, Dresden, DE;
Marie-francoise Gouzy, Allschwil, CH;
Petra Welzel, Dresden, DE;
Inventors:
Carsten Werner, Dresden, DE;
Uwe Freudenberg, Dresden, DE;
Dorit Meinhold, Dresden, DE;
Marie-Francoise Gouzy, Allschwil, CH;
Petra Welzel, Dresden, DE;
Assignee:
Zetascience GmbH, Dresden, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 33/08 (2006.01); A61L 33/10 (2006.01); A61L 33/12 (2006.01); A61K 38/18 (2006.01); A61K 47/42 (2006.01); A61K 47/36 (2006.01); C08B 37/10 (2006.01); C08J 5/18 (2006.01); C08J 3/075 (2006.01); C08B 37/00 (2006.01); C08L 5/10 (2006.01); A61L 27/54 (2006.01); A61L 27/52 (2006.01); C08J 3/24 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61L 2300/414 (2013.01); C08J 5/18 (2013.01); C08J 3/075 (2013.01); C08B 37/0075 (2013.01); C08B 37/0081 (2013.01); C08L 5/10 (2013.01); C08J 2371/02 (2013.01); A61L 27/54 (2013.01); A61L 2300/602 (2013.01); C08J 2305/10 (2013.01); C08J 3/246 (2013.01);
Abstract
The invention relates to a bioactive hydrogel as a hybrid material of heparin and star-branched polyethylene glycol with functionalized end groups, wherein the heparin is bound directly by reaction of the carboxyl groups activated with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimides/N-hydroxysulfosuccinimide (EDC/s-NHS) with the terminal amino groups of the polyethylene glycol covalently by amide bonds.