The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Apr. 26, 2011
Floris Louis Van Delft, Nijmegen, NL;
Floris Petrus Johannes Theodorus Rutjes, Wijchen, NL;
Frederik Jan Dommerholt, Beuningen, NL;
Floris Louis van Delft, Nijmegen, NL;
Floris Petrus Johannes Theodorus Rutjes, Wijchen, NL;
Frederik Jan Dommerholt, Beuningen, NL;
Synaffix B.V., Oss, NL;
Abstract
The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label, and to the use of these conjugates in bioorthogonal labeling, imaging and/or modification, such as for example surface modification, of a target molecule. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.