The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Jul. 23, 2013
Applicants:

Thomas H. Marsilje, San Diego, CA (US);

Wenshuo LU, San Diego, CA (US);

Bei Chen, San Diego, CA (US);

Xiaohui He, San Diego, CA (US);

Christian Cho-hua Lee, San Diego, CA (US);

Songchun Jiang, San Diego, CA (US);

Kunyong Yang, San Diego, CA (US);

Inventors:

Thomas H. Marsilje, San Diego, CA (US);

Wenshuo Lu, San Diego, CA (US);

Bei Chen, San Diego, CA (US);

Xiaohui He, San Diego, CA (US);

Christian Cho-Hua Lee, San Diego, CA (US);

Songchun Jiang, San Diego, CA (US);

Kunyong Yang, San Diego, CA (US);

Assignee:

IRM LLC, Hamilton, BM;

Attorneys:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); A61K 31/506 (2006.01); A61P 35/00 (2006.01); A61K 31/5377 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); A61K 45/06 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/5377 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 403/12 (2013.01); C07D 409/14 (2013.01); A61K 45/06 (2013.01); A61K 31/55 (2013.01); C07D 413/14 (2013.01); A61K 31/506 (2013.01);
Abstract

The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or analplastic lymphoma kinase (ALK).


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