The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Dec. 18, 2012
Applicant:
Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;
Inventors:
Armin Heckel, Biberach an der Riss, DE;
Andreas Blum, Warthausen, DE;
Dieter Hamprecht, Pozzolengo, IT;
Joerg Kley, Mittelbiberach, DE;
Assignee:
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4192 (2006.01); A61K 31/4468 (2006.01); A61K 31/4965 (2006.01); C07D 213/74 (2006.01); C07D 241/16 (2006.01); C07D 403/02 (2006.01); A61K 31/501 (2006.01); C07F 9/6558 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); A61K 45/06 (2006.01); A61K 31/683 (2006.01); A61K 31/497 (2006.01); A61K 31/55 (2006.01); A61K 31/675 (2006.01); C07D 451/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/501 (2013.01); C07F 9/65583 (2013.01); C07D 403/12 (2013.01); C07D 401/14 (2013.01); A61K 45/06 (2013.01); A61K 31/683 (2013.01); A61K 31/497 (2013.01); A61K 31/55 (2013.01); A61K 31/675 (2013.01); C07D 451/04 (2013.01);
Abstract
The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels, the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.