The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Mar. 08, 2011
José Manuel Bartolomé-nebreda, Toledo, ES;
Susana Conde-ceide, Toledo, ES;
Gregor James Macdonald, Zoersel, BE;
Joaquin Pastor-fernández, Toledo, ES;
Michiel Luc Maria Van Gool, Madrid, ES;
María Luz Martín-martín, Salamanca, ES;
Greta Constantia Peter Vanhoof, Zoersel, BE;
José Manuel Bartolomé-Nebreda, Toledo, ES;
Susana Conde-Ceide, Toledo, ES;
Gregor James MacDonald, Zoersel, BE;
Joaquin Pastor-Fernández, Toledo, ES;
Michiel Luc Maria Van Gool, Madrid, ES;
María Luz Martín-Martín, Salamanca, ES;
Greta Constantia Peter Vanhoof, Zoersel, BE;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to novel imidazo[1,2-a]pyrazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.