The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Sep. 10, 2010
Applicants:

David Bumcrot, Belmont, MA (US);

Dinah Wen-yee Sah, Boston, MA (US);

Ivanka Toudjarska, Medford, MA (US);

Jared Gollob, Boston, MA (US);

Akshay Vaishnaw, Arlington, MA (US);

Christina Gamba-vitalo, Cambridge, MA (US);

Inventors:

David Bumcrot, Belmont, MA (US);

Dinah Wen-Yee Sah, Boston, MA (US);

Ivanka Toudjarska, Medford, MA (US);

Jared Gollob, Boston, MA (US);

Akshay Vaishnaw, Arlington, MA (US);

Christina Gamba-Vitalo, Cambridge, MA (US);

Assignee:

Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a SNALP formulation, methods of using the compositions to inhibit the expression of the Eg5/KSP and VEGF, and methods of using the compositions to treat pathological processes mediated by Eg5/KSP and VEGF expression, such as cancer.


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