The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Aug. 23, 2013
Applicant:

Vitrolife Sweden Ab, Kungsbacka, SE;

Inventors:

David K Gardner, Mckinnon, AU;

Mark G Larman, Melbourne, AU;

Donald Linck, Denver, CO (US);

Assignee:

Vitrolife Sweden AB, Göteborg, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 5/073 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0604 (2013.01); C12N 2500/44 (2013.01);
Abstract

A composition and method for in vitro fertilization is provided which uses culture media comprising elevated concentrations of lipoic acid. More specifically, the invention provides culture media for developmental cells having a lipoic acid concentration of 5 μM to 40 μM. Culture media that include lipoic acid at concentrations within the identified range are able to provide blastocysts with increased survival, increased cell numbers, increased inner cell masses and/or increased percentage of the total mass made up by the inner cell compared to blastocysts cultured in a control medium.


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