The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Jul. 01, 2010
Applicants:
Klaus Hahn, Chapel Hill, NC (US);
Yi Wu, Farmington, CT (US);
Brian Kuhlman, Chapel Hill, NC (US);
Inventors:
Assignee:
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01); C12N 1/20 (2006.01); C12N 1/15 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01); G01N 33/542 (2006.01); C12N 9/16 (2006.01);
U.S. Cl.
CPC ...
G01N 33/542 (2013.01); C07K 2319/73 (2013.01); C12N 9/16 (2013.01);
Abstract
The present invention relates to fusion proteins comprising protein light switches and methods of photomanipulating the activity of the proteins. The invention further relates to polynucleotides and vectors encoding the fusion proteins, cells comprising the fusion proteins, and methods of using the fusion proteins to study protein function and analyze subcellular activity, as well as diagnostic and therapeutic methods.