The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Jun. 02, 2009
Applicants:
Jose M. Galarza, Hartsdale, NY (US);
Theresa E. Latham, Mamaroneck, NY (US);
Inventors:
Jose M. Galarza, Hartsdale, NY (US);
Theresa E. Latham, Mamaroneck, NY (US);
Assignee:
Wyeth LLC, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12P 15/00 (2006.01); C12P 7/00 (2006.01); C12P 7/02 (2006.01); C12P 7/04 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C07K 2319/00 (2013.01); C12N 2710/14143 (2013.01); C12N 7/00 (2013.01); C12N 2760/16123 (2013.01); C12N 2760/16122 (2013.01); A61K 2039/5258 (2013.01);
Abstract
Influenza virus-like particles (VLPs) comprising the structural proteins HA, NA, M1 and M2 are described. VLPs are also generated containing M1 alone, as are VLPs with M1 and any one or two of HA, NA and M2. VLPs with HA from one influenza subtype and NA from a different influenza subtype are also described, as are VLPs in which a portion or all of HA or NA is replaced by a heterologous moiety not produced by influenza virus, so as to comprise chimeric VLPs.