The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Aug. 23, 2013
Applicants:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare S.a., Glattpark, CH;

Inventors:

Leo Martis, Long Grove, IL (US);

Mehul Patel, Saunderstown, RI (US);

Joseph A. Giertych, Lake Forest, IL (US);

James W. Mongoven, Long Grove, IL (US);

Jacqueline A. Kunzier, Downers Grove, IL (US);

William F. Owen, Durham, NC (US);

Assignees:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare S.A., Glattpark (Opfikon), CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12G 1/00 (2006.01); C12Q 1/04 (2006.01); A61K 31/716 (2006.01);
U.S. Cl.
CPC ...
A61K 31/716 (2013.01); G01N 2333/4722 (2013.01); C12Q 1/04 (2013.01); Y10S 436/815 (2013.01);
Abstract

Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions are provided. A novel cause of aseptic peritonitis is provided—aseptic peritonitis associated with gram positive microbial contamination of a dialysis solution. Peptidoglycan is a major component of a gram positive bacterial cell wall and thus can serve as a marker for gram positive bacteria. In this regard, testing for peptidoglycans can be utilized to effectively prevent peritonitis in patients that use the peritoneal dialysis solutions, such as peritoneal dialysis solutions that contain a glucose polymer including an icodextrin and the like.


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