The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Oct. 16, 2009
Rudolph Valenta, Vienna, AT;
Ric Van Tol, Nijmegen, NL;
Udo Herz, Kirchhain, DE;
Heidrun Hochwallner, St. Leonhard/Forst, AT;
Margarte Focke-tejkl, Vienna, AT;
Ines Swoboda, Vienna, AT;
Ulrike Schulmeister, Waldhausen, AT;
Rudolph Valenta, Vienna, AT;
Ric Van Tol, Nijmegen, NL;
Udo Herz, Kirchhain, DE;
Heidrun Hochwallner, St. Leonhard/Forst, AT;
Margarte Focke-Tejkl, Vienna, AT;
Ines Swoboda, Vienna, AT;
Ulrike Schulmeister, Waldhausen, AT;
Mead Johnson Nutrition Company, Glenview, IL (US);
Abstract
A method for identifying allergenic proteins and peptides. More specifically, a method for identifying allergenic milk proteins and/or peptides including the steps of: providing at least one expression library comprising DNA or cDNA derived from the mammary gland tissue of a lactating cow, expressing at least one protein or peptide encoded by said expression library, determining the binding capacity of said at least one protein or peptide to IgE of at least one serum of an individual who is sensitive to cow's milk, contacting the at least one protein or peptide exhibiting an IgE binding capacity as determined in step c) with basophil cells, eosinophil cells or mast cells and identifying the at least one protein or peptide as being allergenic when said basophil cells, eosinophil cells or mast cells release upon contact with at least one protein or peptide of step d) at least one mediator.