The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Nov. 18, 2004
Applicants:

Breda Mary Cullen, Skipton, GB;

Sara Jayne Gregory, West Yorkshire, GB;

Inventors:

Breda Mary Cullen, Skipton, GB;

Sara Jayne Gregory, West Yorkshire, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 15/00 (2006.01); A61K 38/08 (2006.01); A61K 38/48 (2006.01); A61L 15/44 (2006.01); A61L 15/32 (2006.01);
U.S. Cl.
CPC ...
A61L 15/44 (2013.01); A61L 2300/45 (2013.01); A61L 2300/604 (2013.01); A61L 15/32 (2013.01); A61L 2300/434 (2013.01); A61L 2300/412 (2013.01);
Abstract

A wound dressing material for controlled activation of a wound healing therapeutic compound in the presence of a protease enzyme in a wound fluid, the material comprising: a medically acceptable polymer; a wound healing therapeutic agent; an inhibitor of the protease enzyme; and a linker group which is cleavable by the protease enzyme, wherein the activities of both the wound healing therapeutic agent and the inhibitor are increased by contacting the wound dressing material with a wound fluid containing the protease enzyme. For example, the enzyme may be a matrix metalloproteinase, the therapeutic agent may be a reactive oxygen scavenger, and the inhibitor may be a tissue inhibitor of metalloproteinase (TIMP).


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