The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Aug. 27, 2010
Applicants:
Michele Pallaoro, Siena, IT;
Derek O'hagan, Cambridge, MA (US);
Rino Rappuoli, Castelnuovo Berardenga, IT;
Inventors:
Michele Pallaoro, Siena, IT;
Derek O'Hagan, Cambridge, MA (US);
Rino Rappuoli, Castelnuovo Berardenga, IT;
Assignee:
Novartis AG, Basel, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/095 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01); A61K 39/108 (2006.01); A61K 39/085 (2006.01); A61K 39/09 (2006.01); A61K 39/155 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 39/0002 (2013.01); A61K 39/0258 (2013.01); A61K 39/085 (2013.01); A61K 39/092 (2013.01); A61K 39/095 (2013.01); A61K 39/155 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); C12N 2760/18534 (2013.01);
Abstract
An immunological adjuvant comprises an aluminum salt, an immunostimulatory oligonucleotide and a polycationic polymer, wherein the oligonucleotide and the polymer ideally associate with each other to form a complex. The adjuvant can be included in a composition with an immunogen e.g. to elicit an immune response that protects against a bacterial disease or a fungal disease.