The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Feb. 19, 2010
Applicant:
Keith L. Knutson, Rochester, MN (US);
Inventor:
Keith L. Knutson, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/385 (2006.01); A61K 45/00 (2006.01); C07K 5/103 (2006.01); C07K 14/74 (2006.01); C12N 5/0783 (2010.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70539 (2013.01); C07K 2319/33 (2013.01); A61K 2039/64 (2013.01); A61K 2039/6031 (2013.01); A61K 39/385 (2013.01); C07K 2319/01 (2013.01); C07K 5/101 (2013.01); C07K 7/08 (2013.01); C12N 2501/998 (2013.01); C07K 2319/50 (2013.01); A61K 2039/5158 (2013.01); C12N 5/0636 (2013.01);
Abstract
The document provides to methods and materials for generating T cells (e.g., antigen-specific CD4T cells). For example, methods and materials for using nested MHC class II epitopes as vaccines to generate activated CD4T cells in vivo or as reagents to generate activated CD4T cells ex vivo are provided.