The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2014

Filed:

Sep. 13, 2013
Applicant:

Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);

Inventors:

Dimiter S. Dimitrov, Rockville, MD (US);

Zhongyu Zhu, Frederick, MD (US);

Christopher C. Broder, Silver Spring, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/10 (2006.01); G01N 33/68 (2006.01); A61K 39/275 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1027 (2013.01); C07K 2317/92 (2013.01); C07K 2316/96 (2013.01); C07K 2317/21 (2013.01); C07K 2317/565 (2013.01); G01N 33/6893 (2013.01);
Abstract

The present invention relates to monoclonal antibodies that bind or neutralize Hendra or Nipah virus. The invention provides such antibodies, fragments of such antibodies retaining Hendra or Nipah virus-binding ability, fully human antibodies retaining Hendra or Nipah virus-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention.


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