The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Oct. 26, 2005
Chengru Zhu, Albuquerque, NM (US);
Edgar Boedeker, Placitas, NM (US);
Chengru Zhu, Albuquerque, NM (US);
Edgar Boedeker, Placitas, NM (US);
Other;
The United States of America as Represented by the Department of Veteran Affairs, Washington, DC (US);
Abstract
The invention provides live, attenuated enterohemorrhagic(EHEC) bacteria in which the Shiga toxin coding sequences are deleted to abolish Shiga toxin production and one or more of the nucleotide sequences for the bacterial adhesin protein intimin, the locus of enterocyte effacement encoded regulator, and the translocated intimin receptor are mutated to inactivate the activity of the encoded protein(s). This live, attenuatedbacteria is used in a vaccine for reducing or inhibiting carriage and shedding of EHEC in cattle.