The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Aug. 11, 2009
Applicants:

Katsuhiko Mikoshiba, Saitama, JP;

Nobuyuki Nukina, Saitama, JP;

Shoichiro Ozaki, Saitama, JP;

Kouzo Hamada, Saitama, JP;

Jun-ichi Goto, Saitama, JP;

Akinobu Suzuki, Saitama, JP;

Etsuko Ebisui, Saitama, JP;

Akiko Terauchi, Saitama, JP;

Inventors:

Katsuhiko Mikoshiba, Saitama, JP;

Nobuyuki Nukina, Saitama, JP;

Shoichiro Ozaki, Saitama, JP;

Kouzo Hamada, Saitama, JP;

Jun-Ichi Goto, Saitama, JP;

Akinobu Suzuki, Saitama, JP;

Etsuko Ebisui, Saitama, JP;

Akiko Terauchi, Saitama, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/00 (2006.01); A61K 31/67 (2006.01); C07F 5/02 (2006.01); A61K 31/69 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 31/69 (2013.01);
Abstract

The present invention provides a protein cross-linking inhibitor containing a compound represented by any of the following formulas (1)-(13), or a pharmaceutically acceptable salt thereof:R—[—X—B(ZR)—Y—B(ZR)—W—]—R,  (1)R—[—X—B(ZR)—Y—]—R,  (2)R—[—B(ZR)—Y—B(ZR)—W—]—R,  (3)R—[—X—B(ZR)—]—R,  (4)R—[—B(ZR)—W—]—R,  (5)R—X—B(ZR)-T[B(ZR)—W—R],  (6)R—B(OH),  (7)R—B(ZR)—X—B(ZR)—R,  (8)R—B(R)—O—B(R)—R,  (9)R—[—X—B(ZR)—Y—B(ZR)—]—R,  (10)R—[—X—B(ZR)—Y—B(ZR)—W-Q-]—R,  (11)R—[—P—X—B(ZR)—Y—B(ZR)—W—]—R,  (12)[R—X—B(ZR)—Y]B(ZR),  (13)wherein each symbol is as defined in the DESCRIPTION.


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