The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Oct. 08, 2013
Applicants:

Lothar Schwink, Frankfurt am Main, DE;

Martin Bossart, Frankfurt am Main, DE;

Heiner Glombik, Frankfurt am Main, DE;

Matthias Gossel, Frankfurt am Main, DE;

Dieter Kadereit, Frankfurt am Main, DE;

Thomas Klabunde, Frankfurt am Main, DE;

Thomas Maier, Frankfurt am Main, DE;

Siegfried Stengelin, Frankfurt am Main, DE;

Inventors:

Lothar Schwink, Frankfurt am Main, DE;

Martin Bossart, Frankfurt am Main, DE;

Heiner Glombik, Frankfurt am Main, DE;

Matthias Gossel, Frankfurt am Main, DE;

Dieter Kadereit, Frankfurt am Main, DE;

Thomas Klabunde, Frankfurt am Main, DE;

Thomas Maier, Frankfurt am Main, DE;

Siegfried Stengelin, Frankfurt am Main, DE;

Assignee:

Sanofi, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); A61K 31/44 (2006.01); A61K 31/497 (2006.01); C07D 401/12 (2006.01); A61K 31/4545 (2006.01); C07D 413/14 (2006.01); A61K 31/4439 (2006.01); C07D 401/14 (2006.01); C07D 407/14 (2006.01); C07D 417/14 (2006.01); C07D 207/12 (2006.01); C07D 405/14 (2006.01); A61K 31/444 (2006.01); A61K 31/4015 (2006.01);
U.S. Cl.
CPC ...
A61K 31/497 (2013.01); C07D 401/12 (2013.01); A61K 31/4545 (2013.01); C07D 413/14 (2013.01); A61K 31/4439 (2013.01); C07D 401/14 (2013.01); C07D 407/14 (2013.01); C07D 417/14 (2013.01); C07D 207/12 (2013.01); A61K 46/06 (2013.01); C07D 405/14 (2013.01); A61K 31/444 (2013.01); A61K 31/4015 (2013.01);
Abstract

The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.


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